I did a thing with the thing

https://soundcloud.com/mikeholyfieldmusic/statx9

it was kinda difficult on my macbook laptop, i need a mou5 i think. but super fun none the less.
to me sounds like some mangled sound waves with a huge pitch envelope and vowel filters and fx

this is the best skrillex type tutorial i've found it's on cinema but maybe you can get ideas from it

https://www.youtube.com/watch?v=TPP-kxD4Rh4
he's good, really good. dude can write a clean beat. I think most of his production is sample based tho. not an insult, just artists that are more synthesis based tend to be more innovative with sound design. just an opinion i could be totally wrong. just i think his lead sounds are samples repitche...